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Microbead (research)
Microbeads are uniform polymer particles, typically 0.5 to 500 micrometres in diameter. Bio-reactive molecules can be absorbed or coupled to their surface, and used to separate biological materials such as cells, proteins, or nucleic acids.
Microbeads are used for isolation and handling of specific material or molecules, as well as for analyzing sensitive molecules, or those that are in low abundance, e.g. in miniaturized and automated settings.
==Background==
Microbeads were created when the late Dr. John Ugelstad managed to form polystyrene beads of the same spherical sizes at the University of Trondheim, Norway in 1976. He then created superparamagnetic microbeads (Dynabeads). These beads exhibit magnetic properties when placed in a magnetic field, with no residual magnetism when removed from the magnetic field, thereby leading to the development of magnetic separation technology.
Microbeads enable fast liquid-phase kinetics, and display a large surface area per volume. Microbeads can execute rapid separation throughout the application protocol by applying a magnet. Other processes such as centrifugation, filtration, columns or precipitation, are not needed.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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